SGLT
SGLT are a family of glucose transporter found in the intestinal mucosa (enterocytes) of the small intestine (SGLT1) and the proximal tubule of the nephron (SGLT2 in PCT and SGLT1 in PST). They contribute to renal glucose reabsorption. In the kidneys, 100% of the filtered glucose in the glomerulus has to be reabsorbed along the nephron (98% in PCT, via SGLT2). If the plasma glucose concentration is too high (hyperglycemia), glucose is excreted in urine (glucosuria) because SGLT are saturated with the filtered glucose.
-
E4CPG是Group I/group II mGlu 拮抗剂。
More
-
DMeOB是 mGlu5的阴性变构调节剂（negative allosteric modulator）。
More
-
DL-AP3是Group I mGlu 拮抗剂。
More
-
DFB
EI0964
DFB是mGlu5变构的增强剂(allosteric potentiator)。
More
-
Desmethyl-YM 298198是mGlu1拮抗剂YM 298198 的衍生物。
More
-
E4CPG是Group I/group II mGlu 拮抗剂。
More
-
DMeOB是 mGlu5的阴性变构调节剂（negative allosteric modulator）。
More
-
DL-AP3是Group I mGlu 拮抗剂。
More
-
DFB
EI0964
DFB是mGlu5变构的增强剂(allosteric potentiator)。
More
-
Desmethyl-YM 298198是mGlu1拮抗剂YM 298198 的衍生物。
More
-
E4CPG是Group I/group II mGlu 拮抗剂。
More
-
DMeOB是 mGlu5的阴性变构调节剂（negative allosteric modulator）。
More
-
DL-AP3是Group I mGlu 拮抗剂。
More
-
DFB
EI0964
DFB是mGlu5变构的增强剂(allosteric potentiator)。
More
-
Desmethyl-YM 298198是mGlu1拮抗剂YM 298198 的衍生物。
More
